DAB2, DAB adaptor protein 2, 1601

N. diseases: 107; N. variants: 11
Disease: Chronic Kidney Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.120 Biomarker group BEFREE Together, these data suggest that Dab2 plays a versatile role in the kidney and may impact on acute and CKDs.-Schütte-Nütgen, K., Edeling, M., Mendl, G., Krahn, M. P., Edemir, B., Weide, T., Kremerskothen, J., Michgehl, U., Pavenstädt, H. Getting a Notch closer to renal dysfunction: activated Notch suppresses expression of the adaptor protein Disabled-2 in tubular epithelial cells. 30052485 2019
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.120 AlteredExpression group BEFREE Functional experiments confirmed that reducing Dab2 expression in renal tubules protected mice from CKD. 30275566 2018
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.120 GeneticVariation group GWASDB Genome-wide association and functional follow-up reveals new loci for kidney function. 22479191 2012
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.120 GeneticVariation group GWASDB New loci associated with kidney function and chronic kidney disease. 20383146 2010