DAP, death associated protein, 1611

N. diseases: 144; N. variants: 7
Disease: Lambert-Eaton Myasthenic Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022972
Disease: Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton Myasthenic Syndrome 		0.040 Biomarker disease BEFREE <b>Data Synthesis:</b> Prior to the approval of amifampridine, 3,4-DAP was first-line for the management of LEMS symptoms. 31319693 2020
CUI: C0022972
Disease: Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton Myasthenic Syndrome 		0.040 Biomarker disease BEFREE In the muscle, a likely target region of 3,4-DAP in LEMS patients, the Kp was higher than in the plasma. 31419315 2019
CUI: C0022972
Disease: Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton Myasthenic Syndrome 		0.040 Biomarker disease BEFREE The possibility of obtaining marketing authorization of orphan pharmaceutical compounding preparations: 3,4-DAP for Lambert-Eaton Myasthenic Syndrome. 29191521 2018
CUI: C0022972
Disease: Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton Myasthenic Syndrome 		0.040 Biomarker disease BEFREE These findings predict 3,4-DAP is most effective in conditions with low probability of quantal release, such as Lambert-Eaton myasthenic syndrome. 27251582 2017