DAXX, death domain associated protein, 1616

N. diseases: 137; N. variants: 2
Disease: Neuroendocrine Tumors ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 Biomarker group BEFREE Performance of DAXX Immunohistochemistry as a Screen for DAXX Mutations in Pancreatic Neuroendocrine Tumors. 30747827 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 GeneticVariation group BEFREE DAXX mutations as potential genomic markers of malignant evolution in small nonfunctioning pancreatic neuroendocrine tumors. 31819132 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 GeneticVariation group BEFREE DAXX Mutation Status of Embolization-Treated Neuroendocrine Tumors Predicts Shorter Time to Hepatic Progression. 30342802 2018
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 Biomarker group BEFREE Alternative lengthening of telomeres and ATRX/DAXX loss can be reliably detected in FNAs of pancreatic neuroendocrine tumors. 28371511 2017
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 Biomarker group BEFREE DAXX/ATRX and MEN1 genes are strong prognostic markers in pancreatic neuroendocrine tumors. 28591701 2017
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 Biomarker group BEFREE A lack of ATRX or DAXX in a sellar NET suggests a nonpituitary NET, probably of pancreatic origin. 28719461 2017
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 Biomarker group BEFREE In this study, we analyzed the expression of the candidate genes mammalian target of rapamycin (mTOR), alpha thalassemia/mental retardation syndrome X-linked (ATRX), and death domain-associated protein (DAXX) to investigate the specific oncogenetics and potential therapeutic options for ileal NETs. 25439321 2015
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 Biomarker group BEFREE These results support the hypothesis that DAXX- and ATRX-negative tumors are a more aggressive subtype of pNET, and could lead to identification of strategies to target CIN in pancreatic tumors. 24148618 2014
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors 		0.380 Biomarker group CTD_human DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. 21252315 2011