|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
DBH is also involved in the pathophysiology of alcoholism.
|
24201835 |
2014 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
DBH effects were confirmed [odds ratio (OR) = 0.7, P = 0.04] after controlling for associated clinical variables (MD severity, OR = 3.4, P < 0.001; antisocial personality disorder, OR = 2.2, P < 0.001; alcohol dependence, OR = 1.4, P = 0.05; and nicotine dependence, OR = 1.4, P = 0.06).
|
24521142 |
2014 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
DBH effects were confirmed [odds ratio (OR) = 0.7, P = 0.04] after controlling for associated clinical variables (MD severity, OR = 3.4, P < 0.001; antisocial personality disorder, OR = 2.2, P < 0.001; alcohol dependence, OR = 1.4, P = 0.05; and nicotine dependence, OR = 1.4, P = 0.06).
|
24521142 |
2014 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The present study aimed to evaluate the association of alcohol dependence and alcohol dependence-related phenotypes with platelet monoamine oxidase type B (MAO-B) activity, Val108/158Met of catechol-o-methyltransferase (COMT), variable number of tandem repeats (VNTR) in the third exon of dopamine receptor D4 (DRD4) gene, VNTR in the 3'-untranslated region of dopamine transporter (DAT) gene, -1021C/T of dopamine beta-hydroxylase (DBH) and MAO-B intron 13 polymorphisms.
|
25035107 |
2014 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Polymorphisms in the aldehyde dehydrogenase 2 and dopamine β hydroxylase genes are not associated with Alzheimer's disease.
|
24201835 |
2014 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
The present study aimed to evaluate the association of alcohol dependence and alcohol dependence-related phenotypes with platelet monoamine oxidase type B (MAO-B) activity, Val108/158Met of catechol-o-methyltransferase (COMT), variable number of tandem repeats (VNTR) in the third exon of dopamine receptor D4 (DRD4) gene, VNTR in the 3'-untranslated region of dopamine transporter (DAT) gene, -1021C/T of dopamine beta-hydroxylase (DBH) and MAO-B intron 13 polymorphisms.
|
25035107 |
2014 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
This study presents evidence for a potentially functional DBH variant influencing the risk for alcohol dependence while other comorbid conditions are not independently influenced by this SNP.
|
23906995 |
2013 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
This study presents evidence for a potentially functional DBH variant influencing the risk for alcohol dependence while other comorbid conditions are not independently influenced by this SNP.
|
23906995 |
2013 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Genes SSTR4, ALDH1L2, GAD1, DBH and GABRP may participate in the biological process of alcohol dependence.
|
23857790 |
2013 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Genes SSTR4, ALDH1L2, GAD1, DBH and GABRP may participate in the biological process of alcohol dependence.
|
23857790 |
2013 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
DBH*444G/A polymorphism of the dopamine-beta-hydroxylase gene is associated with alcoholism but not with severe alcohol withdrawal symptoms.
|
16252068 |
2006 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The DBH -1021 C/T polymorphism is not associated with alcoholism but possibly with patients' exposure to life events.
|
16133787 |
2005 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
Biomarker
|
disease |
BEFREE |
Studies combining genotyping at DBH with biochemical measurement of plasma DbetaH have proven useful in studies of schizophrenia, cocaine-induced paranoia (CIP), depression, attention deficit hyperactivity disorder, and alcoholism.
|
15088079 |
2004 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Our study investigated whether the DBH-1021C-->T polymorphism and plasma DbetaH activity were associated with alcoholism or with delirium tremens (DT) during alcohol withdrawal by analyzing 207 German alcoholic and 102 healthy control subjects.
|
12488060 |
2002 |
|
Alcoholic Intoxication, Chronic
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The differences between FHP and FHN groups on correlations between DBH and peak intoxication or usual drinking history raise speculations that the "normal" (FHN) relationship between alcohol intake and plasma DBH activity may be impaired in individuals at high risk (FHP) for the future development of alcoholism.
|
7349621 |
1981 |