DBH, dopamine beta-hydroxylase, 1621

N. diseases: 202; N. variants: 26
Disease: Congestive heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.020 AlteredExpression disease BEFREE The aim of the present study was to evaluate the effects of zamicastat, a novel DβH inhibitor that decreases noradrenaline and increases dopamine levels in peripheral sympathetically innervated tissues, on the hemodynamic and cardiometabolic parameters in salt-induced hypertension and heart failure in the Dahl salt-sensitive (SS) rat. 30401628 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.020 Biomarker disease BEFREE Etamicastat is a dopamine β-hydroxylase (DβH) inhibitor currently in clinical development for the treatment of hypertension and heart failure. 24296323 2013