|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Comparing patients with ESRD (IgAN-ESRD) and those without ESRD (IgAN-non ESRD), there was a significant increase only in the ACE DD genotype (P < 0.05) among the four gene polymorphisms.
|
21163122 |
2010 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This study was designed to evaluate the angiotensin-converting enzyme insertion/deletion (ACE-I/D), angiotensinogen (AGT) M235T, and angiotensin II receptor type 1 (ATR1) A1166C and type 2 (ATR2) C3123A gene polymorphisms as risk factors for progression to ESRD in patients with VUR.Methods.
|
19288324 |
2009 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our data also suggest that an interaction effect may exist between ACE (I/D) and eNOS (G894 --> T) polymorphism in increasing the risk of vascular complications in ESRD patients.
|
18629615 |
2008 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
To elucidate this issue, we investigated the relationship between the insertion (I) and deletion (D) ACE gene polymorphism and rapidity of progression of FSGS to ESRD in Iranian children.
|
19076285 |
2008 |
|
Kidney Failure, Chronic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The common mechanism is probably through lower levels of ACE, glomerular pressure and proteinuria resulting in reduced renal damage and retardation of progression to ESRF.
|
17601378 |
2007 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The results disclosed that the ACE polymorphism had a slight influence on the age of onset of ESRD in ADPKD patients and the NOS3 and BDKBR1 polymorphisms showed a very slight involvement in renal outcome.
|
17303584 |
2007 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The study suggests that genetic testing of the I/D polymorphism in patients with nephropathy before initiating ACE therapy will most likely be cost-effective, even if the risk for II carriers to develop ESRD when treated with ACE inhibitors is only 1.4% higher than for DD carriers.
|
17429318 |
2007 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our data suggest that losartan provides a similar short-term antiproteinuric response for all three genotypes of ACE I/D genotype in non-diabetic proteinuric chronic renal disease.
|
16960460 |
2006 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
An angiotensin converting enzyme haplotype predicts survival in patients with end stage renal disease.
|
16791616 |
2006 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Six patients with steroid-resistant nephrotic syndrome went into end stage renal disease; ACE genotype was I/I in one and I/D in five, but none were D/D.
|
17199794 |
2006 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the distribution of angiotensin converting enzyme (ACE), angiotensinogen (AGT) and angiotensin receptor type 1 (ATR1) genetic polymorphisms in children affected by chronic renal failure due to renal hypodysplasia associated with posterior urethral valves or without urethral abnormalities.
|
16006956 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
There was no significant relationship detected between the D allele of ACE, the C allele of AT1R or the T allele of AGT genes and response to steroid therapy, extent of renal dysfunction and the progression to ESRD.
|
16525944 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Polymorphism of the ACE Gene in dialysis patients: overexpression of DD genotype in type 2 diabetic end-stage renal failure patients.
|
16385653 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We analyzed clinical parameters and ACE genotype distribution between type 2 diabetic patients at the extremes of renal risk, i.e. an end-stage renal failure (ESRF) group (n = 103, group 1) who were on dialysis therapy due to progression of diabetic nephropathy, and a no progression group (n = 88, group 2) who had maintained normal renal function and normoalbuminuria for more than 15 years.
|
16385653 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
BEFREE |
The role of interaction of polymorphisms in the Renin-Angiotensin-System (RAS) with angiotensin converting enzyme (ACE) or angiotensin receptor (AGTR1) inhibitors (RAS inhibitors) is unknown, as is the role of such therapy in end stage renal disease (ESRD) patients.
|
15946912 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Twelve-lead electrocardiograms (ECGs), serum electrolytes (sodium, potassium, and calcium), and ACE and angiotensin II levels were obtained 10 to 12 hours after a hemodialysis session in 43 patients with ESRD on chronic hemodialysis [mean age (+/-SD), 55 +/- 14 years].
|
16105049 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Given the effect of angiotensin-converting enzyme inhibitors on the progression of both diabetic and non-diabetic renal disease, we hypothesized that the polymorphisms of NAD(P)H oxidase are associated with development of end-stage renal disease (ESRD).
|
16215641 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
LHGDN |
Polymorphisms of ACE and AT1R genes additively contribute to QTc prolongation found in a great majority of ESRD patients.
|
16105049 |
2005 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
ACE gene polymorphism does not have a significant effect on the development of ESRD and the prevalence of LVH in patients with ADPKD.
|
14600431 |
2004 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
ACE gene polymorphism, left ventricular geometry, and mortality in diabetic patients with end-stage renal disease.
|
15036826 |
2004 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The linked ACE T-A-T-A-A-I allele was observed significantly more frequently in VUR children with ESRD (P<0.001).
|
15045574 |
2004 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This study compared the polymorphisms of angiotensin-converting enzyme (ACE), angiotensinogen (AGT) and angiotensin II type 1 receptor (AT1R) gene between type II diabetes with diabetic nephropathy (DN) in end-stage renal disease (ESRD) and those of the normal individuals in Taiwan.
|
12728975 |
2003 |
|
Kidney Failure, Chronic
|
0.600 |
Therapeutic
|
disease |
RGD |
Although compelling evidence of a beneficial effect exists for the use of angiotensin-converting enzyme inhibitors (ACEIs) and low-protein diets, there is little evidence on whether carbon adsorbent has an effect on retardation of the progression of CRF.
|
14586729 |
2003 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In this large series of ADPKD patients, we found no effect of the ACE (I/D) polymorphism on the age at ESRD, either alone or in combination with the G460W polymorphism of ADD.
|
13679477 |
2003 |
|
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The ACE genotypes did not differ among the groups of slow progressors (27.1% I/I, 44.8% I/D and 28.1% D/D), pts with ESRF before 63 years of age (23.6% I/I, 51.4% I/D and 25% D/D) and rapid progressors (20% I/I, 55% I/D and 25% D/D).
|
12697976 |
2003 |