ACE, angiotensin I converting enzyme, 1636

N. diseases: 101; N. variants: 18
Disease: IGA Glomerulonephritis ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.400 Biomarker disease CTD_human We examined whether the M235T polymorphism of the angiotensinogen (AGT) gene, the insertion/deletion polymorphism of the angiotensin-converting enzyme (ACE) gene, and the A1166--> C polymorphism of the angiotensin II type 1 receptor gene may be associated with disease progression in 168 Caucasian patients with IgA nephropathy. 9259580 1997
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.400 Biomarker disease CTD_human The results indicate that deletion polymorphism in the ACE gene, particularly the homozygote DD, is a risk factor for progression to chronic renal failure in IgA nephropathy. 7593601 1995