ACE, angiotensin I converting enzyme, 1636

N. diseases: 101; N. variants: 18
Disease: Kidney Failure, Chronic ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.600 Biomarker disease CTD_human The DD genotype of the ACE gene polymorphism is associated with progression of diabetic nephropathy to end stage renal failure in IDDM. 10099885 1999
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.600 Biomarker disease CTD_human The results indicate that deletion polymorphism in the ACE gene, particularly the homozygote DD, is a risk factor for progression to chronic renal failure in IgA nephropathy. 7593601 1995