ACE, angiotensin I converting enzyme, 1636

N. diseases: 101; N. variants: 18
Disease: Depressed mood ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.400 Biomarker phenotype PSYGENET Variants of the ACE gene influence cortisol secretion and appear as susceptibility factors for late-life depression in the elderly population. 24193727 2013
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.400 Biomarker phenotype PSYGENET Association of angiotensin-converting enzyme (ACE) gene polymorphism with elevated serum ACE activity and major depression in an Iranian population. 22688325 2012
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.400 Biomarker phenotype PSYGENET We detected intensive DNA methylation within a recently described, functional important region of the ACE gene promoter including hypermethylation in depressed patients (p = 0.008) and a significant inverse correlation between the ACE serum concentration and ACE promoter methylation frequency in the total sample (p = 0.02). 22808171 2012