ACE, angiotensin I converting enzyme, 1636

N. diseases: 1082; N. variants: 82
Disease: Acute Coronary Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE For patients with acute coronary syndrome (ACS) treated with percutaneous coronary intervention (PCI), it is unclear whether angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) are associated with reduced mortality, particularly with preserved left ventricular ejection fraction (LVEF). 31105064 2020
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE Genetic polymorphism of angiotensin converting enzyme and angiotensin II type 1 receptors and their impact on the outcome of acute coronary syndrome. 31195108 2020
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 Biomarker disease BEFREE Guidelines previously recommended use of dual antiplatelet therapy, statins, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ACEI/ARB) and beta blockers (five classes of drugs) in patients without contraindications or intolerance after acute coronary syndrome (ACS). 31255479 2019
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 Biomarker disease BEFREE Coenzyme Q10 Modulates Remodeling Possibly by Decreasing Angiotensin-Converting Enzyme in Patients with Acute Coronary Syndrome. 30044377 2018
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE Assessment of the rs4340 ACE gene polymorphism in acute coronary syndrome in a Western Mexican population. 28973758 2017
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 Biomarker disease BEFREE The secondary prevention treatment for acute coronary syndrome (ACS) is based on the combined use of drugs from four therapeutic classes (beta-blockers, antiplatelet agents, statins, and angiotensin-converting enzyme inhibitors or angiotensin receptor blockers). 28124399 2017
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE Angiotensin converting enzyme DD genotype is associated with acute coronary syndrome severity and sudden cardiac death in Taiwan: a case-control emergency room study. 22333273 2012
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE In this case-control study, we determine the frequency of mutant alleles in the ACE I/D, M235T and A1166C polymorphisms in postmenopausal Caucasian women with and without a diagnosis of acute coronary syndrome (ACS). 16274774 2005
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE We determined the ACE genotype in 152 Japanese patients with acute coronary syndromes and 399 healthy individuals. 9322984 1997
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE The II genotype of the angiotensin-converting enzyme gene delays the onset of acute coronary syndromes. 9327770 1997
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE Logistic regression analysis showed that ACE polymorphism affected the development of acute coronary syndrome in recessive pattern of D allele. 9364295 1997
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.100 GeneticVariation disease BEFREE Our results indicate that, in contrast to previous reports in Japanese patients, no association exists between angiotensin-converting enzyme gene polymorphism and the development of restenosis in Caucasian patients with acute coronary syndromes.) 8623745 1996