Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.060 AlteredExpression disease BEFREE Down-regulation of GADD45A enhances chemosensitivity in melanoma. 29515153 2018
CUI: C0025202
Disease: melanoma
melanoma 		0.060 AlteredExpression disease BEFREE Most experimental conditions resulted in lower expression of p21, GADD45A, and PUMA, and a higher expression of CDC2 in melanomas. 21691232 2011
CUI: C0025202
Disease: melanoma
melanoma 		0.060 Biomarker disease BEFREE Gadd45a activation protects melanoma cells from ultraviolet B-induced apoptosis. 17703175 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.060 AlteredExpression disease LHGDN These observations suggest that Gadd45a inactivation could be a useful way to sensitize melanoma cells to chemotherapy. 17703175 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.060 Biomarker disease LHGDN GADD45 and GADD153 were positive in 60% and 80% of primary melanomas, respectively. 12168790 2002
CUI: C0025202
Disease: melanoma
melanoma 		0.060 Biomarker disease BEFREE GADD45 was observed in 8/29 oral melanomas and cell positivity averaged 2.8%. 10757041 2000
CUI: C0025202
Disease: melanoma
melanoma 		0.060 Biomarker disease BEFREE Our conclusion is that GADD proteins play an important role in the malignant transformation of naevus to melanoma and GADD 45 and GADD 153 proteins can influence patient survival. 9413226 1998