DHX9, DExH-box helicase 9, 1660

N. diseases: 54; N. variants: 0
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.010 Biomarker disease BEFREE There are no respiratory dehydrogenases other than NDH-2 to feed electrons into the respiratory chain, and there is only one respiratory oxygen reductase to reduce oxygen to water.Although <i>S. agalactiae</i> grows well in <i>vitro</i> by fermentative metabolism, it is shown here that the absence of NDH-2 results in attenuated virulence, as observed by reduced colonization in heart and kidney in a mouse model of systemic infection. 29970468 2018