DEFB4A, defensin beta 4A, 1673

N. diseases: 177; N. variants: 0
Disease: Inflammatory Bowel Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		0.050 Biomarker group BEFREE Differential induction in different IBD entities suggests different clinical response patterns based on still unknown hBD2-associated mechanisms. 30150730 2018
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		0.050 Biomarker group BEFREE Here we show that SAP-1 ablation in interleukin (IL)-10-deficient mice, a model of inflammatory bowel disease, resulted in a marked increase in the severity of colitis in association with up-regulation of mRNAs for various cytokines and chemokines in the colon. 26195794 2015
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		0.050 Biomarker group BEFREE Dysregulation of human beta-defensin-2 protein in inflammatory bowel disease. 19617917 2009
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		0.050 AlteredExpression group LHGDN Human beta defensin 2 promotes intestinal wound healing in vitro. 18449938 2008
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases 		0.050 AlteredExpression group BEFREE Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease. 12169983 2002