GLIS3, GLIS family zinc finger 3, 169792

N. diseases: 105; N. variants: 48
Disease: Thyroid Hyalinizing Trabecular Adenoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1336751
Disease: Thyroid Hyalinizing Trabecular Adenoma
Thyroid Hyalinizing Trabecular Adenoma 		0.020 Biomarker disease BEFREE Our data provide evidence to suggest that the PAX8-GLIS3 fusion is pathognomonic for hyalinizing trabecular tumors, and that the presence of the PAX8-GLIS3 fusion in thyroid neoplasms may be used as an ancillary marker for the diagnosis of hyalinizing trabecular tumor, thereby avoiding overtreatment in case of misdiagnoses with apparently similar malignant tumors. 31273314 2019
CUI: C1336751
Disease: Thyroid Hyalinizing Trabecular Adenoma
Thyroid Hyalinizing Trabecular Adenoma 		0.020 Biomarker disease BEFREE This study demonstrates that GLIS rearrangements, particularly PAX8-GLIS3, are highly prevalent in HTT but not in PTC. 30648929 2019