DHPS, deoxyhypusine synthase, 1725

N. diseases: 62; N. variants: 1
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 Biomarker disease BEFREE All together, our results show for the first time that downregulation of eIF5A through inhibition of DHS altered the physiopathology and observed immune outcome of diabetes in an animal model that closely resembles human T1D. 24496311 2014
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 Biomarker disease BEFREE These data are relevant in light of the fact that GC7 is considered a potent and selective inhibitor of DHS and is a potential candidate drug for cancer, diabetes and HIV therapy. 25218134 2014