|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
NQO1 expression was not associated with clinical outcome in adenocarcinoma.
|
30868898 |
2019 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The NQO1 protein showed a mainly cytoplasmic staining pattern in lung cancer cells, including adenocarcinoma and squamous cell carcinoma (SCC).
|
25880877 |
2015 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
LHGDN |
NQO1 expression in pancreatic cancer and its potential use as a biomarker.
|
18091324 |
2008 |
|
Adenocarcinoma
|
0.100 |
GeneticVariation
|
group |
LHGDN |
The NAD(P)H:quinone oxidoreductase I C609T polymorphism modifies the risk of Barrett esophagus and esophageal adenocarcinoma.
|
17575500 |
2007 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Higher levels of NQO1 expression were demonstrated in pancreatic adenocarcinomas (0.831 +/- 0.021) compared to those in nontumorous tissues from nonsmokers (0.139 +/- 0.024).
|
16532285 |
2006 |
|
Adenocarcinoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The frequency of the NQO1 609TT genotype, reported to be associated with null enzyme activity, was higher in individuals with all cases and SCC than in the healthy controls (OR = 1.97, 95% CI = 1.06-3.66, P = 0.032; and OR = 2.42, 95% CI = 1.21-4.82, P = 0.012; respectively), but not in ADC/ADSC cases.
|
15661231 |
2005 |
|
Adenocarcinoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In conclusion, determination of the NQO1 genotype may gain importance as a stratification marker in future prevention trials for adenocarcinoma of upper gastrointestinal tract.
|
14506737 |
2003 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
LHGDN |
Benzo(a)pyrene activates extracellular signal-related and p38 mitogen-activated protein kinases in HT29 colon adenocarcinoma cells: involvement in NAD(P)H:quinone reductase activity and cell proliferation.
|
12383707 |
2002 |
|
Adenocarcinoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The result indicates that the NQO1-Pro/Pro and GSTT1-null genotypes are risk factors for lung adenocarcinoma development, and that the genetic factors for susceptibility to adenocarcinoma are different from those to squamous cell carcinoma.
|
12163326 |
2002 |
|
Adenocarcinoma
|
0.100 |
GeneticVariation
|
group |
LHGDN |
The result indicates that the NQO1-Pro/Pro and GSTT1-null genotypes are risk factors for lung adenocarcinoma development, and that the genetic factors for susceptibility to adenocarcinoma are different from those to squamous cell carcinoma.
|
12163326 |
2002 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
BEFREE |
When cases were stratified according to histological subtypes, the wild-type NQO1 was more common in adenocarcinoma than in controls.
|
10591487 |
1999 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
A point mutation in the mRNA of NADP(H): quinone oxidoreductase 1 (NQO1, DT-diaphorase) is believed to be responsible for reduced enzyme activity in the adenocarcinoma BE cell line.
|
7669561 |
1995 |