NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.050 GeneticVariation disease BEFREE In the stratified analysis based on cancer types, significant associations were observed between NQO1 C609T polymorphism and GC (OR = 1.38, 95% CI = 1.11-1.72, p = 0.003) and CRC (OR = 1.18, 95% CI = 1.06-1.30, p = 0.001), but not with EC (OR = 1.16, 95% CI = 0.99-1.35, p = 0.06). 29652514 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.050 GeneticVariation disease BEFREE We conclude that the NQO1 gene C609T polymorphism increases the risk for gastric cancer, especially in Asian populations. 24716985 2014
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.050 GeneticVariation disease BEFREE We conclude that the NQO1 gene C609T polymorphism increases the risk for gastric cancer, especially in Asian populations. 22911602 2012
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.050 AlteredExpression disease BEFREE DTD mRNA was also down-regulated in primary gastric cancer with TCF-3 up-regulation. 11085512 2000
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.050 Biomarker disease BEFREE DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines. 8665520 1996