DIO3, iodothyronine deiodinase 3, 1735

N. diseases: 80; N. variants: 1
Disease: Neoplasm Metastasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.320 Biomarker phenotype CTD_human MAPK and SHH pathways modulate type 3 deiodinase expression in papillary thyroid carcinoma. 26825960 2016
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.320 Biomarker phenotype BEFREE DLK1-DIO3 cluster miRNAs are elevated in the serum of patients with metastatic cancer. 25324143 2014
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.320 Biomarker phenotype BEFREE These results establish the DLKI-DIO3 miRNA cluster as a critical checkpoint regulating tumor growth and metastasis and implicate epigenetic modification of the cluster in driving tumor progression. 23105110 2012