DIO3, iodothyronine deiodinase 3, 1735

N. diseases: 80; N. variants: 1
Disease: Depressed mood ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.020 Biomarker phenotype BEFREE Mice with adult DIO3 deficiency did not show significant differences in growth, serum thyroid hormone parameters or behaviors related to anxiety and depression. 31561084 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.020 AlteredExpression phenotype BEFREE The expression of DIO1 on mRNA/protein levels in the rDD patients was reduced in comparison to the control subjects, while the expression of DIO3 was higher in the patients suffering from depression. 29182613 2017