DLG2, discs large MAGUK scaffold protein 2, 1740

N. diseases: 44; N. variants: 28
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Comparative genomics of spontaneous human and dog osteosarcomas (OS) expose Disks Large Homolog 2 (DLG2) as a tumor suppressor candidate. 30093633 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 GeneticVariation group BEFREE Beyond TP53, the RB1, ATRX, and DLG2 genes showed recurrent somatic alterations in 29%-53% of the tumors. 24703847 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 GeneticVariation group BEFREE A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A. 7590743 1995