DNASE1, deoxyribonuclease 1, 1773

N. diseases: 180; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.020 Biomarker disease BEFREE Treatment with DNase I completely diminished the exaggerated atherosclerosis. 29673593 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.020 GeneticVariation disease BEFREE We therefore examined common variants in the human ACSL1 locus by genetic association studies for fasting glucose, diabetes status, and preclinical atherosclerosis by using the MAGIC and DIAGRAM consortia; followed by analyses in participants from the Multi-Ethnic Study of Atherosclerosis, the Penn-T2D consortium, and a meta-analysis of subclinical atherosclerosis in African Americans; and finally, expression quantitative trait locus analysis and identification of DNase I hypersensitive sites (DHS). 26711138 2016