DNASE1, deoxyribonuclease 1, 1773

N. diseases: 180; N. variants: 8
Disease: Pneumonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.020 Biomarker disease BEFREE These results reveal an essential function of STING-mediated self-dsDNA sensing after silica exposure, and identify DNase I as a potential therapy for silica-induced lung inflammation. 30523277 2018
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.020 Biomarker disease BEFREE As expected, DNase I, an inhibitor of MPO and NADPH, decreased pulmonary inflammation and NETs. 30622526 2018