DNASE2, deoxyribonuclease 2, lysosomal, 1777

N. diseases: 29; N. variants: 6
Disease: Anemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia 		0.020 Biomarker disease BEFREE Most Dnase1 and Dnase2 family members are poorly characterized, yet their elimination can lead to a wide range of diseases, including lethal anemia, parakeratosis, cataracts and systemic lupus erythematosus. 28666955 2017
CUI: C0002871
Disease: Anemia
Anemia 		0.020 Biomarker disease BEFREE DNase II(-/-) embryos suffer from lethal anemia due to IFN-beta produced in the macrophages carrying undigested DNA. 20706988 2010