DNASE2, deoxyribonuclease 2, lysosomal, 1777

N. diseases: 29; N. variants: 6
Disease: Lupus Erythematosus, Systemic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.330 Biomarker disease BEFREE We describe a 17-year-old boy with DNase II deficiency, presenting a clinical picture with significant overlap with systemic lupus erythematosus. 31448075 2020
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.330 Biomarker disease BEFREE Most Dnase1 and Dnase2 family members are poorly characterized, yet their elimination can lead to a wide range of diseases, including lethal anemia, parakeratosis, cataracts and systemic lupus erythematosus. 28666955 2017
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.330 Biomarker disease GENOMICS_ENGLAND Type I interferon-mediated autoinflammation due to DNase II deficiency. 29259162 2017
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.330 Biomarker disease BEFREE Genetic associations of DNase II with SLE and related phenotypes were examined in Korean patients with SLE. 15723160 2005