DNM2, dynamin 2, 1785

N. diseases: 178; N. variants: 30
Disease: Thrombocytopenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia 		0.010 Biomarker phenotype BEFREE Dnm2fl/f PF4-Cre (Dnm2<sup>Plt-/-</sup>) mice specifically lacking dynamin 2 within the platelet lineage developed severe thrombocytopenia and bleeding diathesis and Dnm2Plt platelets adhered poorly to collagen under arterial shear rates. 31296575 2019