DNMT1, DNA methyltransferase 1, 1786

N. diseases: 496; N. variants: 36
Disease: Colonic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.520 Biomarker group BEFREE Levels of DNA methyltransferase 1 (DNMT1) and protein arginine methyltransferase 6 (PRMT6) were increased in colon tumors from Ppara<sup>ΔIE</sup> mice, compared with colon tumors from control mice. 31154022 2019
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.520 AlteredExpression group BEFREE The DNMT1 protein was overexpressed in colon tumours from patients compared to non-malignant mucosa from the same patients (P = 0.02). 30663502 2018
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.520 Biomarker group CTD_human Further, 5-azacytidine potentiated cisplatin induced antitumor activity by involving decreased expression of pAKT, DNMT1 and an increased expression of p38 in colon tumors. 19723570 2009
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.520 Therapeutic group RGD Further, 5-azacytidine potentiated cisplatin induced antitumor activity by involving decreased expression of pAKT, DNMT1 and an increased expression of p38 in colon tumors. 19723570 2009