DNMT3A, DNA methyltransferase 3 alpha, 1788

N. diseases: 350; N. variants: 56
Disease: Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.120 AlteredExpression disease BEFREE We herein demonstrated that miR-29s effectively blocked DNMT3A and 3B expression by degrading their mRNAs in U87MG glioblastoma cell line. 25625222 2015
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.120 AlteredExpression disease BEFREE Thus, we speculate that DNMT3a decreased expression may be involved in the early post-natal inheritance of an epigenetically altered NPC population that could be responsible for glioblastoma development later in adult life. 17653095 2008
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.120 GeneticVariation disease CLINVAR