DPYD, dihydropyrimidine dehydrogenase, 1806

N. diseases: 249; N. variants: 101
Disease: Stage III Colon Cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278480
Disease: Stage III Colon Cancer
Stage III Colon Cancer 		0.020 GeneticVariation disease BEFREE In the current study, we assessed DPYD variants suggested to correlate with 5-FU toxicity, a deep intronic variant (c.1129-5923 C>G), and four variants within a haplotype (hapB3) in 1953 stage III colon cancer patients who received adjuvant FOLFOX±cetuximab. 26658227 2016
CUI: C0278480
Disease: Stage III Colon Cancer
Stage III Colon Cancer 		0.020 AlteredExpression disease BEFREE Expression of TS and DPD proteins is not predictive for survival in patients with stage III colon cancer treated adjuvantly with 5-FU regimens. 16012177 2005