|
Drug usage
|
0.070 |
GeneticVariation
|
phenotype |
BEFREE |
The prevalence of risky alcohol consumption (AUDIT) and associations with depressive symptoms (PHQ-9), problematic drug use (DUDIT), adherence to ART (CASE Adherence Index), sexual behaviour and demographic characteristics were assessed among both patient groups independently.
|
31664572 |
2019 |
|
Drug usage
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
However, providers tended to emphasize individual level barriers to ART, such as lack of motivation due to drug use, whereas PWID highlighted health systems barriers, such as clinic hours and financial burden, fears, and side effects.
|
30306437 |
2019 |
|
Drug usage
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Any drug use, relative to no drug use, was associated with fewer HIV care visits (IRR 0.50, 95% CI [0.30, 0.85]), but did not significantly impact ART adherence, or attaining an undetectable viral load.
|
31187356 |
2019 |
|
Drug usage
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
The majority of patients met more than one exclusion criteria with the most frequent criteria for exclusion being a non-approved ART regimen (58 and 47% respectively), having a psychiatric disorder (52%), active alcohol or injection drug use (27%), having an HIV viral load > 50 copies/ml (15%), a CrCl < 60 ml/min (13%) and a history of decompensated cirrhosis (13%).
|
31053098 |
2019 |
|
Drug usage
|
0.070 |
GeneticVariation
|
phenotype |
BEFREE |
Chemsex drug use has been associated with increased HIV transmission risk among gay, bisexual and other men who have sex with men (GBM) and poor ART adherence among people living with HIV.
|
31739177 |
2019 |
|
Drug usage
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Among STR users, compared to no drug use, substance use overall remained detrimental to ART adherence (aPR = 1.61, 95% CI 1.24-2.09); specifically, both marijuana (aPR = 1.48, 95% CI: 1.11-1.97) and other drug use (aPR = 1.87, 95% CI 1.29-2.70) predicted suboptimal adherence.
|
28560499 |
2018 |
|
Drug usage
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Multivariable analysis including age, race, sex, HIV-1 RNA, prior antiretroviral therapy, probable route of infection, prior ADE, absolute CD4, and %CD4 was performed; prior ART (P<.0001), injection-drug use (P=.04), lower absolute CD4 (P=.002), and lower %CD4 (P=.002) predicted disease progression.
|
17205482 |
2007 |