DRD1, dopamine receptor D1, 1812

N. diseases: 181; N. variants: 8
Disease: Hypotension ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020649
Disease: Hypotension
Hypotension 		0.300 Biomarker phenotype CTD_human Enhanced hypotensive response to intravenous apomorphine in chronic spinalized, conscious rats: role of spinal dopamine D(1) and D(2) receptors. 12946566 2003
CUI: C0020649
Disease: Hypotension
Hypotension 		0.300 Biomarker phenotype CTD_human In anesthetized rats, intrathecal (i.t.) administration, at the upper thoracic level of the spinal cord of fenoldopam (a selective dopamine D1-receptor agonist) or quinpirole (a selective D2-receptor agonist) decreased blood pressure (BP) and heart rate (HR) in a dose-dependent manner. 1724532 1991