DRD1, dopamine receptor D1, 1812

N. diseases: 181; N. variants: 8
Disease: Impulsive Behavior ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		0.050 GeneticVariation phenotype BEFREE In regard to impulsivity and aggressiveness, rs4532 of DRD1 was significantly associated with UPPS-P score. 31559529 2019
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		0.050 Biomarker phenotype BEFREE These data support a role of DRD1 in opioid DD and impulsive behaviors. 31192519 2019
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		0.050 Biomarker phenotype BEFREE This study confirms that dopamine D1 receptor plays an essential role in modulation of impulsive behavior, as measured by the 5-CSRTT. 30393121 2018
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		0.050 Biomarker phenotype BEFREE Muscarinic M4 Receptors on Cholinergic and Dopamine D1 Receptor-Expressing Neurons Have Opposing Functionality for Positive Reinforcement and Influence Impulsivity. 29740282 2018
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		0.050 GeneticVariation phenotype BEFREE We examined the potential association between heroin dependence and 8 single-nucleotide polymorphisms (rs686, rs4867798, rs1799914, rs4532, rs5326, rs265981, rs10078714, rs10078866) of DRD1, and the associations between single single-nucleotide polymorphism, haplotypes, and impulsive behavior. 25966176 2015