DRD1, dopamine receptor D1, 1812

N. diseases: 181; N. variants: 8
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.210 GeneticVariation disease BEFREE Here we report that the ros mutant mice harboring a recessive mutation in the Slc35d3 gene show obesity and MetS and reduced membrane dopamine receptor D1 (D1R) with impaired dopamine signaling in striatal neurons. 24550737 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.210 Therapeutic disease RGD Mitogen-activated protein kinase upregulation reduces renal D1 receptor affinity and G-protein coupling in obese rats. 17191082 2007
CUI: C0028754
Disease: Obesity
Obesity 		0.210 Biomarker disease RGD Here, we test the hypothesis that renal dopamine D1 receptor dysfunction in obese Zucker rats is caused by oxidative stress. 15983225 2005