DRD1, dopamine receptor D1, 1812

N. diseases: 181; N. variants: 8
Disease: Impaired cognition ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 Biomarker disease BEFREE In summary, administration of the dopamine D1 receptor agonist SKF81297 into the PAG alleviated morphine-exposure-induced cognitive impairments. 30660614 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 Biomarker disease BEFREE A genetic association exists between DRD1 gene and impaired cognition in BD. 25233244 2015
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 Biomarker disease BEFREE The dopamine 1 receptor (DRD1) is thought to mediate some of the cognitive deficits in SCZ, including impairment of working memory that relies on normal dorsolateral prefrontal cortex (DLPFC) function. 24322206 2014
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.040 Biomarker disease BEFREE HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance-dependent and substance-independent populations. 24078558 2013