|
Drug Dependence
|
0.400 |
Biomarker
|
group |
BEFREE |
The D2 dopamine receptor (Drd2) is implicated in several brain disorders such as schizophrenia, Parkinson's disease, and drug addiction.
|
30604007 |
2019 |
|
Drug Dependence
|
0.400 |
Biomarker
|
group |
BEFREE |
The dopamine D2 receptor (DRD2) and dopamine transporter (DAT) play a regulatory role in dopaminergic neurotransmission and thus play an important role in drug addiction.
|
31330230 |
2019 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Polymorphism of the dopamine D2 receptor TaqIA gene is related to reward response, relapse risks and effect of therapy for drug addiction.
|
30928885 |
2019 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The aim of the study was to determine relationships between the selected DRD2 gene polymorphisms and drug addiction.
|
30659563 |
2018 |
|
Drug Dependence
|
0.400 |
Biomarker
|
group |
BEFREE |
Reward- and memory-related candidate genes dopamine D2 receptor (DRD2) and brain-derived neurotrophic factor (BDNF), as well as the opioid receptor genes (OPRM1, OPRD1, and OPRK1), have been implicated in drug dependence, but relatively little is known on their contributions to heroin dependence in populations worldwide.
|
28692418 |
2017 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Growing evidence indicated conflicting results about the dopamine receptor D2 (DRD2)/kinase domain containing 1 gene (ANKK1) TaqIA single nucleotide polymorphism (rs1800497) and common illicit drug dependence risk including stimulants, opioid and marijuana.
|
25500252 |
2015 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Drug addiction polymorphisms such as the TaqI A1 allele of the dopamine D2 receptor (DRD2) are associated with cocaine, alcohol, and opioid use, but few studies have linked DRD2 to food craving.
|
23670889 |
2013 |
|
Drug Dependence
|
0.400 |
Biomarker
|
group |
BEFREE |
Here, we will review the information collected implicating the receptors of the D1 family (DRD1 and DRD5) and of the D2 family (DRD2, DRD3 and DRD4) in drug addiction.
|
19179847 |
2009 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Finally, opioid dosage requirements may be increased depending on the risk of drug addiction (e.g., DRD2 polymorphisms decreasing the functioning of the dopaminergic reward system).
|
19615406 |
2009 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Many association studies of DRD2 and substance dependence (SD), including alcohol dependence (AD) and drug dependence (DD), have been reported; the results have been inconsistent.
|
18828801 |
2008 |
|
Drug Dependence
|
0.400 |
Biomarker
|
group |
CTD_human |
Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward.
|
16901644 |
2006 |
|
Drug Dependence
|
0.400 |
Biomarker
|
group |
BEFREE |
It has been shown that the dopamine D2 receptor (DRD2) gene dysfunction is associated with multi-drug addiction.
|
15704216 |
2005 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Because positive association between DRD2 alleles and alcohol and/or drug dependence has been reported only in populations of European ancestry, we limited the present study to European Americans (EAs).
|
11054774 |
2000 |
|
Drug Dependence
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The Taq A1 variant of the human DRD2 gene has been associated with drug addiction, some forms of severe alcoholism, and other impulsive, addictive behaviours.
|
8807661 |
1996 |