|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Variants of the DRD2 Taq1A polymorphism, which have been shown to result in functional differences in dopamine D2 receptors (D2R), have been linked to various externalizing outcomes in adults.
|
30264459 |
2019 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In adults, the Taq1a polymorphism (rs1800497) near the D2 receptor (DRD2) gene is associated with body mass index and binge eating and is more prevalent among non-Hispanic Blacks (NHB) and Hispanic-Americans (HA) relative to non-Hispanic Whites (NHW).
|
30253082 |
2019 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Research in healthy adults suggests that C957T polymorphism of the dopamine D2 receptor encoding DRD2 and the Taq1A polymorphism of the neighbouring gene ankyrin repeat and kinase domain containing 1 (ANKK1) alter dopaminergic signalling and may influence prefrontally-mediated executive functions.
|
30836122 |
2019 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We investigated the influence of A1 allele of the TAQ1A polymorphism in DRD2 receptor gene region on mortality in alcohol-dependent individuals in an 18-year follow-up.
|
29236941 |
2018 |
|
Taq1A POLYMORPHISM
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CYP2D6 metabolic activity correlates independently from DRD2 Taq1A polymorphism with hospital stay duration.
|
29930225 |
2018 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, the A1A1 genotype of DRD2 Taq1A polymorphism was significantly more common among WD patients with rigidity.
|
29992511 |
2018 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The -141C Ins/Del and Taq1A polymorphism in the dopamine D2 receptor gene may confer susceptibility to schizophrenia in Asian populations.
|
27283386 |
2016 |
|
Taq1A POLYMORPHISM
|
0.100 |
Biomarker
|
disease |
BEFREE |
Eighteen cocaine users, 18 pathological gamblers and 18 controls performed a probabilistic reversal learning task during functional magnetic resonance imaging, and were genotyped for the DRD2/ANKK Taq1A polymorphism.
|
26045346 |
2015 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, the extent to which this hypothesized relationship was moderated by genetic risk (Taq1A polymorphism in the DRD2/ANKK1 gene cluster) and verbal fluency as an indicator of executive cognitive ability (Controlled Oral Word Association Test) was also examined.
|
24629326 |
2014 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of the current study was to determine whether, in a large population-based sample, there are associations between adiposity and (i) the A1 (T) allele of the Taq1A polymorphism (rs1800497) in DRD2 and (ii) the G allele of the A118G polymorphism (rs1799971) in OPRM1.
|
23917806 |
2014 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The effect of the ANKK1/DRD2 Taq1A polymorphism on weight changes of dopaminergic treatment in prolactinomas.
|
23740147 |
2014 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.
|
23683269 |
2013 |
|
Taq1A POLYMORPHISM
|
0.100 |
Biomarker
|
disease |
BEFREE |
A number of studies have analyzed the association between the Taq1A polymorphism (located in the gene cluster ANKK1/DRD2) and AD.
|
23203481 |
2013 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Sensation Seeking was elevated in carriers of the low-function allele of the DRD2 Taq1A polymorphism who also reported childhood sexual abuse, relative to that in individuals showing other combinations of alleles and abuse exposures.
|
22733030 |
2012 |
|
Taq1A POLYMORPHISM
|
0.100 |
Biomarker
|
disease |
BEFREE |
We examined the effects of the Taq1A polymorphism on the plasma monoamine metabolites during the treatment of schizophrenia with aripiprazole, a DRD2 partial agonist.
|
22198450 |
2012 |
|
Taq1A POLYMORPHISM
|
0.100 |
Biomarker
|
disease |
BEFREE |
The -141C Ins/Del, but not Taq1A, polymorphism of the DRD2 gene was significantly associated with sexual dysfunction with the del allele being less frequent in sexual dysfunction subjects.
|
21749219 |
2011 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to examine relationships between the dopamine D2 receptor gene (DRD2) Taq1A polymorphism (rs1800497), a serotonin transporter gene (SLC6A4) polymorphism (5-HTTLPR), coping motives, and adolescents' binge drinking and alcohol-related problems.
|
21244440 |
2011 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Carrying the A1 allele of the dopamine D2 receptor (DRD2) gene Taq1A polymorphism (rs1800497) is associated with reduced dopamine D2 receptor availability in the brain.
|
19925838 |
2010 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Research implicates the A1 allele of the dopamine D2 receptor gene (DRD2) Taq1A polymorphism in the development of depression and anxiety.
|
20526230 |
2010 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our results do not support an association between the DRD2 rs1800497 (Taq1A) polymorphism and response to NRT, contrary to our previous study.
|
19273465 |
2009 |
|
Taq1A POLYMORPHISM
|
0.100 |
Biomarker
|
disease |
BEFREE |
Available evidence does not support an association between the DRD2 Taq1A polymorphism and smoking behavior.
|
19246443 |
2009 |
|
Taq1A POLYMORPHISM
|
0.100 |
Biomarker
|
disease |
BEFREE |
When the subjects were grouped by the DRD2 Taq1A polymorphism, there were no significant differences among the three Taq1A genotypes.
|
19396436 |
2009 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Carrying the A1 allele at the dopamine receptor D2 (DRD2) Taq1A polymorphism site moderated the effects of withdrawal on nogo P3 amplitude, suggesting the A1 allele is a vulnerability marker for withdrawal-related attentional deficits.
|
19220487 |
2009 |
|
Taq1A POLYMORPHISM
|
0.100 |
Biomarker
|
disease |
BEFREE |
The results suggest an association between the DRD2 Taq1A polymorphism status and the variation in the clinical response to aripiprazole.
|
18786813 |
2008 |
|
Taq1A POLYMORPHISM
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials.
|
18058343 |
2007 |