DRD3, dopamine receptor D3, 1814

N. diseases: 199; N. variants: 13
Disease: Addictive Behavior ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE Selective dopamine D3 receptor antagonists modulate the improvement of psychostimulant addiction and relapse. 30257450 2018
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE The dopamine receptor D3 (DRD3) gene, one of the candidate genes for amphetamine dependence (AD), is involved in the mesolimbic dopaminergic system, implicated as the underlying mechanism of addiction. 28028606 2018
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE Our results corroborate previous findings reporting the involvement of DRD3 receptor in addictions. 25266122 2015
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE Another receptor, the D3 dopamine receptor (DRD3), may be of additional interest since it is specifically located in the limbic area, and in particular in the nucleus accumbens which plays a significant role in the reward process of addiction behavior. 8825889 1995