DRD3, dopamine receptor D3, 1814

N. diseases: 199; N. variants: 13
Disease: MAJOR AFFECTIVE DISORDER 9 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2700440
Disease: MAJOR AFFECTIVE DISORDER 9
MAJOR AFFECTIVE DISORDER 9 		0.060 GeneticVariation disease BEFREE Possible involvement of the dopamine D3 receptor locus in subtypes of bipolar affective disorder. 10909128 2000
CUI: C2700440
Disease: MAJOR AFFECTIVE DISORDER 9
MAJOR AFFECTIVE DISORDER 9 		0.060 GeneticVariation disease BEFREE We have performed a case-control analysis of dopamine D2-like receptor (DRD2, DRD3 and DRD4) gene polymorphisms in 118 Han Chinese cases with bipolar affective disorder and 196 control subjects, and replication analysis in 157 English cases and 143 control subjects. 10482338 1999
CUI: C2700440
Disease: MAJOR AFFECTIVE DISORDER 9
MAJOR AFFECTIVE DISORDER 9 		0.060 Biomarker disease BEFREE No evidence of association between dopamine D3 receptor gene and bipolar affective disorder. 9129711 1997
CUI: C2700440
Disease: MAJOR AFFECTIVE DISORDER 9
MAJOR AFFECTIVE DISORDER 9 		0.060 GeneticVariation disease BEFREE We have used both approaches to test for possible associations between alleles of the dopamine D3 receptor gene and bipolar affective disorder. 7573178 1995
CUI: C2700440
Disease: MAJOR AFFECTIVE DISORDER 9
MAJOR AFFECTIVE DISORDER 9 		0.060 Biomarker disease BEFREE The dopamine D3 receptor gene: no association with bipolar affective disorder. 8098068 1993
CUI: C2700440
Disease: MAJOR AFFECTIVE DISORDER 9
MAJOR AFFECTIVE DISORDER 9 		0.060 GeneticVariation disease BEFREE Thus, this substitution, which is the first sequence variation identified in the dopamine D3 receptor gene altering the amino acid sequence of the protein, can be regarded as a protein variant with no major effect on the susceptibility to bipolar affective disorder. 8493294 1993