DRD4, dopamine receptor D4, 1815

N. diseases: 189; N. variants: 7
Disease: Alcohol Use Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.020 Biomarker disease BEFREE One candidate gene investigated due to its association with AUD is the dopamine D4 receptor gene (DRD4), which contains a 48-base pair variable number tandem repeat (VNTR) in exon 3 of its coding region. 31149768 2019
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.020 GeneticVariation disease BEFREE These data converge with other recent gene-environment interaction findings implicating the DRD4 polymorphism in the development of alcohol use disorders, and results suggest a specific pathway by which social factors may increase risk for problematic drinking among 7-repeat carriers. 22347363 2012