DRD4, dopamine receptor D4, 1815

N. diseases: 189; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042693
Disease: Violence
Violence
0.020 Biomarker phenotype BEFREE Three dopamine genes (DAT1, DRD2, and DRD4) have been associated with interpersonal delinquency, aggression, and violence when individuals experience adverse environmental exposures. 29294665 2020
CUI: C0042693
Disease: Violence
Violence
0.020 GeneticVariation phenotype BEFREE We examined the interactions between three dopamine gene alleles (DAT1, DRD2, DRD4) previously associated with violent behavior and two components of the adolescent environment (exposure to violence, school social environment) to predict adulthood physical intimate partner violence (IPV) perpetration among white men and women. 28264032 2017