JAG1, jagged canonical Notch ligand 1, 182

N. diseases: 420; N. variants: 63
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.340 Biomarker group BEFREE The in vitro and in vivo results concordantly confirmed a role for endothelial Jagged1 to promote breast tumor through notch activation. 25380486 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.340 Biomarker group CTD_human Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation. 21036696 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.340 AlteredExpression group LHGDN JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. 17990101 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.340 AlteredExpression group LHGDN Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. 17984306 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.340 AlteredExpression group LHGDN A study on Notch signaling in human breast cancer. 17822320 2007