DRP2, dystrophin related protein 2, 1821

N. diseases: 8; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.030 GeneticVariation disease BEFREE We have previously demonstrated that the DRP-2 gene is associated with susceptibility to schizophrenia, but not to bipolar disorders. 17105906 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.030 Biomarker disease BEFREE DRP-2 is an important molecule in guiding neuronal development and its gene is located in 8p21, a chromosomal region that was previously shown to have significant linkage to schizophrenia and to several deficit symptoms of schizophrenia. 15858820 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.030 GeneticVariation disease BEFREE Our results suggest that the *2236C allele in the 3'UTR of the DRP-2 gene, or an unknown mutation in linkage disequilibrium with this allele, may reduce the susceptibility to schizophrenia, especially the paranoid subtype. 12679234 2003
CUI: C0152025
Disease: Polyneuropathy
Polyneuropathy 		0.010 GeneticVariation disease BEFREE Whole exome sequencing revealed a novel dystrophin-related protein-2 (<i>DRP2</i>) deletion in an Iranian family with symptoms of polyneuropathy. 31217940 2019
CUI: C0007959
Disease: Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth Disease 		0.010 GeneticVariation disease BEFREE Absence of Dystrophin Related Protein-2 disrupts Cajal bands in a patient with Charcot-Marie-Tooth disease. 26227883 2015
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.010 GeneticVariation disease BEFREE We have previously demonstrated that the DRP-2 gene is associated with susceptibility to schizophrenia, but not to bipolar disorders. 17105906 2006
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders 		0.010 GeneticVariation group BEFREE No significant association of the DRP-2 gene with METH psychosis was found. 17105906 2006
CUI: C0036349
Disease: Paranoid Schizophrenia
Paranoid Schizophrenia 		0.010 GeneticVariation disease BEFREE The polymorphism *2236T>C in the 3' untranslated region of the DRP-2 gene, which has been shown to be a negative genetic risk factor for paranoid-type schizophrenia, was analyzed in 198 patients with METH psychosis and 221 corresponding healthy controls in a Japanese population. 17105906 2006
CUI: C0036939
Disease: Shared Paranoid Disorder
Shared Paranoid Disorder 		0.010 GeneticVariation disease BEFREE Therefore, we hypothesized that a certain genetic variant of the DRP-2 gene may affect individual vulnerability to the development of METH-induced psychosis. 17105906 2006
CUI: C0349204
Disease: Nonorganic psychosis
Nonorganic psychosis 		0.010 GeneticVariation disease BEFREE No significant association of the DRP-2 gene with METH psychosis was found. 17105906 2006