DRP2, dystrophin related protein 2, 1821

N. diseases: 8; N. variants: 0
Disease: Schizophrenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.030 GeneticVariation disease BEFREE We have previously demonstrated that the DRP-2 gene is associated with susceptibility to schizophrenia, but not to bipolar disorders. 17105906 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.030 Biomarker disease BEFREE DRP-2 is an important molecule in guiding neuronal development and its gene is located in 8p21, a chromosomal region that was previously shown to have significant linkage to schizophrenia and to several deficit symptoms of schizophrenia. 15858820 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.030 GeneticVariation disease BEFREE Our results suggest that the *2236C allele in the 3'UTR of the DRP-2 gene, or an unknown mutation in linkage disequilibrium with this allele, may reduce the susceptibility to schizophrenia, especially the paranoid subtype. 12679234 2003