E2F1, E2F transcription factor 1, 1869
N. diseases: 324; N. variants: 7
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.370 | Biomarker | group | BEFREE | We integrate gene expression profiles of cancer cell lines from two E2F1-driven highly aggressive bladder and breast tumors, and use network analysis methods to identify the tumor type-specific core of the network. | 28775339 | 2017 | ||||
|
0.370 | Biomarker | group | BEFREE | Transcripts regulated by HER2 signaling are highly enriched with E2F1 binding sites and define a gene signature associated with proliferative breast tumor subtypes, cell-cycle progression, and DNA replication. | 26833126 | 2016 | ||||
|
0.370 | Biomarker | group | LHGDN | Evidence of a tumour suppressive function of E2F1 gene in human breast cancer. | 18751386 | 2008 | ||||
|
0.370 | Biomarker | group | LHGDN | Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation. | 17550982 | 2007 | ||||
|
0.370 | AlteredExpression | group | LHGDN | Low E2F1 transcript levels are a strong determinant of favorable breast cancer outcome. | 17535433 | 2007 | ||||
|
0.370 | Biomarker | group | LHGDN | Breast tumor copy number aberration phenotypes and genomic instability. | 16620391 | 2006 | ||||
|
0.370 | Biomarker | group | LHGDN | ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. | 15169882 | 2004 | ||||
|
0.370 | Biomarker | group | CTD_human | E2F1 expression is related with the poor survival of lymph node-positive breast cancer patients treated with fluorouracil, doxorubicin and cyclophosphamide. | 14672398 | 2003 |