E2F1, E2F transcription factor 1, 1869

N. diseases: 324; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3672440
Disease: Bile duct hyperplasia
Bile duct hyperplasia
0.010 Biomarker disease BEFREE We identified a set of important regulatory transcription factors of dark genes for all most-DILI compounds including E2F1 and JUND with supporting evidences in literature and we found <i>Magee1</i> correlated with chemically induced bile duct hyperplasia and adverse responses at 29 days in rats <i>in vivo</i>. 30515189 2018