E2F3, E2F transcription factor 3, 1871

N. diseases: 98; N. variants: 4
Disease: Ewings sarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0553580
Disease: Ewings sarcoma
Ewings sarcoma 		0.020 AlteredExpression disease BEFREE Consequently we propose that aberrant cell cycle activation in Ewing sarcoma is due to the de-repression of E2F targets as a consequence of transcriptional induction and physical recruitment of E2F3 by EWS-FLI1 replacing E2F4 on their target promoters. 25712098 2015
CUI: C0553580
Disease: Ewings sarcoma
Ewings sarcoma 		0.020 Biomarker disease BEFREE Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer. 23940108 2013