GPR183, G protein-coupled receptor 183, 1880

N. diseases: 30; N. variants: 4
Disease: Encephalomyelitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014070
Disease: Encephalomyelitis
Encephalomyelitis 		0.030 Biomarker disease BEFREE We recently showed that these ligands are upregulated in the CNS in experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis and that EBI2 enhanced early infiltration of encephalitogenic T cells into the CNS. 29689289 2018
CUI: C0014070
Disease: Encephalomyelitis
Encephalomyelitis 		0.030 Biomarker disease BEFREE Nonetheless, EBI2 was dispensable in active EAE. 28147280 2017
CUI: C0014070
Disease: Encephalomyelitis
Encephalomyelitis 		0.030 Biomarker disease BEFREE We previously showed that memory CD4<sup>+</sup> T lymphocytes migrate specifically in response to 7α,25-dihydroxycholesterol (7α,25-OHC) via EBI2 in the MS murine model experimental autoimmune encephalomyelitis. 28052250 2017