ECM1, extracellular matrix protein 1, 1893

N. diseases: 120; N. variants: 17
Disease: Ulcerative Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease BEFREE This study aims to determine the relationship between ECM1 gene rs3737240 single nucleotide polymorphism (SNP) and UC in a group of Turkish patients. 28699600 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease BEFREE Despite our large sequencing approach, we could not identify protein altering variants in the genes HNF4A, ECM1, CDH1 and LAMB1 which could explain an impaired intestinal barrier function in UC. 26512799 2015
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 Biomarker disease BEFREE Notably, genes implicated in mucosal barrier function (ECM1, CDH1, HNF4α, and laminin B1) confer risk of UC; furthermore, E-cadherin is the first genetic correlation between colorectal cancer and UC. 21319274 2011
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease BEFREE In contrast, ECM1 rs13294 was not associated with either CD or UC. 21049557 2010
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease BEFREE We found 12 SNPs tagging ten loci, including HLA-DRA, IL10, IL23R, JAK2, S100Z, ARPC2, and ECM1, to be associated with UC. 19861958 2010
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease BEFREE IL10 and ECM1 are associated with UC, while inherited variation at the HLA region is related to an inflammatory colonic phenotype. 19817673 2009
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease BEFREE Furthermore, the recently identified UC locus at ECM1 requires formal testing for association with CD. 19068216 2009
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease BEFREE Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. 18438406 2008
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 Biomarker disease CTD_human Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. 18438406 2008
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.380 GeneticVariation disease LHGDN Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. 18438406 2008