ABCA1, ATP binding cassette subfamily A member 1, 19

N. diseases: 291; N. variants: 116
Disease: Cognition Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders 		0.030 Biomarker group BEFREE In APP transgenic mice, lack of Abca1 increased Aβ deposition and cognitive deficits. 28241068 2017
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders 		0.030 Biomarker group BEFREE ABCA1 Deficiency Affects Basal Cognitive Deficits and Dendritic Density in Mice. 28106559 2017
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders 		0.030 Biomarker group BEFREE These data indicate that ABCA1-induced lipidation of ApoE is necessary for the ability of bexarotene to clear hippocampal soluble Aβ and ameliorate cognitive deficits. 26175148 2016