S1PR1, sphingosine-1-phosphate receptor 1, 1901

N. diseases: 126; N. variants: 6
Disease: Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 AlteredExpression disease BEFREE A recent study uncovered a possible explanation for why patients with glioblastoma often have low levels of circulating T cells: The cells become sequestered in the bone marrow in high numbers, and are likely unable to leave because they lack the S1P1 receptor. 30185625 2018
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 AlteredExpression disease BEFREE Immunohistochemistry for SphK1 and S1P1 confirmed the overexpression in glioblastoma. 24903384 2014