S1PR1, sphingosine-1-phosphate receptor 1, 1901

N. diseases: 126; N. variants: 6
Disease: Secondary malignant neoplasm of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0153676
Disease: Secondary malignant neoplasm of lung
Secondary malignant neoplasm of lung 		0.020 AlteredExpression disease BEFREE Overexpression of S1PR1 promoted subcutaneous xenograft growth and pulmonary metastases, and enhanced expression of EMT markers. 30453284 2018
CUI: C0153676
Disease: Secondary malignant neoplasm of lung
Secondary malignant neoplasm of lung 		0.020 GeneticVariation disease BEFREE We found that genetic deletion of the S1P receptor 1 (<i>S1pr1</i>) alone in CD11b<sup>hi</sup> CD206<sup>+</sup> TAMs infiltrating mouse breast tumors prevents pulmonary metastasis and tumor lymphangiogenesis. 28739604 2017